Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China

From 2014 to 2015, three cases of highly pathogenic avian influenza infection occurred in zoo-housed north-east China tigers (Panthera tigris ssp.altaica) and four tigers died of respiratory distress in succession in Yunnan Province, China. We isolated and characterized three highly pathogenic avian...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Tingsong, Zhao, Huanyun, Zhang, Yan, Zhang, Wendong, Kong, Qiang, Zhang, Zhixiao, Cui, Qinghua, Qiu, Wei, Deng, Bo, Fan, Quanshui, Zhang, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861906/
https://www.ncbi.nlm.nih.gov/pubmed/27162026
http://dx.doi.org/10.1038/srep25845
_version_ 1782431274002022400
author Hu, Tingsong
Zhao, Huanyun
Zhang, Yan
Zhang, Wendong
Kong, Qiang
Zhang, Zhixiao
Cui, Qinghua
Qiu, Wei
Deng, Bo
Fan, Quanshui
Zhang, Fuqiang
author_facet Hu, Tingsong
Zhao, Huanyun
Zhang, Yan
Zhang, Wendong
Kong, Qiang
Zhang, Zhixiao
Cui, Qinghua
Qiu, Wei
Deng, Bo
Fan, Quanshui
Zhang, Fuqiang
author_sort Hu, Tingsong
collection PubMed
description From 2014 to 2015, three cases of highly pathogenic avian influenza infection occurred in zoo-housed north-east China tigers (Panthera tigris ssp.altaica) and four tigers died of respiratory distress in succession in Yunnan Province, China. We isolated and characterized three highly pathogenic avian influenza A(H5N1) viruses from these tigers. Phylogenetic analysis indicated that A/tiger /Yunnan /tig1404 /2014(H5N1) belongs to the provisional subclade 2.3.4.4e which were novel reassortant influenza A (H5N1) viruses with six internal genes from avian influenza A (H5N2) viruses. The HA gene of the isolated A/tiger /Yunnan /tig1412 /2014(H5N1) virus belongs to the subclade 2.3.2.1b. The isolated A/tiger /Yunnan /tig1508/2015 (H5N1) virus was a novel reassortant influenza A (H5N1) virus with three internal genes (PB2, PB1 and M) from H9N2 virus and belongs to the subclade 2.3.2.1c.
format Online
Article
Text
id pubmed-4861906
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-48619062016-05-20 Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China Hu, Tingsong Zhao, Huanyun Zhang, Yan Zhang, Wendong Kong, Qiang Zhang, Zhixiao Cui, Qinghua Qiu, Wei Deng, Bo Fan, Quanshui Zhang, Fuqiang Sci Rep Article From 2014 to 2015, three cases of highly pathogenic avian influenza infection occurred in zoo-housed north-east China tigers (Panthera tigris ssp.altaica) and four tigers died of respiratory distress in succession in Yunnan Province, China. We isolated and characterized three highly pathogenic avian influenza A(H5N1) viruses from these tigers. Phylogenetic analysis indicated that A/tiger /Yunnan /tig1404 /2014(H5N1) belongs to the provisional subclade 2.3.4.4e which were novel reassortant influenza A (H5N1) viruses with six internal genes from avian influenza A (H5N2) viruses. The HA gene of the isolated A/tiger /Yunnan /tig1412 /2014(H5N1) virus belongs to the subclade 2.3.2.1b. The isolated A/tiger /Yunnan /tig1508/2015 (H5N1) virus was a novel reassortant influenza A (H5N1) virus with three internal genes (PB2, PB1 and M) from H9N2 virus and belongs to the subclade 2.3.2.1c. Nature Publishing Group 2016-05-10 /pmc/articles/PMC4861906/ /pubmed/27162026 http://dx.doi.org/10.1038/srep25845 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Hu, Tingsong
Zhao, Huanyun
Zhang, Yan
Zhang, Wendong
Kong, Qiang
Zhang, Zhixiao
Cui, Qinghua
Qiu, Wei
Deng, Bo
Fan, Quanshui
Zhang, Fuqiang
Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title_full Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title_fullStr Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title_full_unstemmed Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title_short Fatal influenza A (H5N1) virus Infection in zoo-housed Tigers in Yunnan Province, China
title_sort fatal influenza a (h5n1) virus infection in zoo-housed tigers in yunnan province, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861906/
https://www.ncbi.nlm.nih.gov/pubmed/27162026
http://dx.doi.org/10.1038/srep25845
work_keys_str_mv AT hutingsong fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT zhaohuanyun fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT zhangyan fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT zhangwendong fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT kongqiang fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT zhangzhixiao fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT cuiqinghua fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT qiuwei fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT dengbo fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT fanquanshui fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina
AT zhangfuqiang fatalinfluenzaah5n1virusinfectioninzoohousedtigersinyunnanprovincechina

Ejemplares similares