Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains

Sweet and umami tastes are perceived by T1r taste receptors in oral cavity. T1rs are class C G-protein coupled receptors (GPCRs), and the extracellular ligand binding domains (LBDs) of T1r1/T1r3 and T1r2/T1r3 heterodimers are responsible for binding of chemical substances eliciting umami or sweet ta...

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Detalles Bibliográficos
Autores principales: Nango, Eriko, Akiyama, Shuji, Maki-Yonekura, Saori, Ashikawa, Yuji, Kusakabe, Yuko, Krayukhina, Elena, Maruno, Takahiro, Uchiyama, Susumu, Nuemket, Nipawan, Yonekura, Koji, Shimizu, Madoka, Atsumi, Nanako, Yasui, Norihisa, Hikima, Takaaki, Yamamoto, Masaki, Kobayashi, Yuji, Yamashita, Atsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861910/
https://www.ncbi.nlm.nih.gov/pubmed/27160511
http://dx.doi.org/10.1038/srep25745

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