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Muc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori binding
The gastrointestinal tract is lined by a thick and complex layer of mucus that protects the mucosal epithelium from biochemical and mechanical aggressions. This mucus barrier confers protection against pathogens but also serves as a binding site that supports a sheltered niche of microbial adherence...
Autores principales: | Magalhães, Ana, Rossez, Yannick, Robbe-Masselot, Catherine, Maes, Emmanuel, Gomes, Joana, Shevtsova, Anna, Bugaytsova, Jeanna, Borén, Thomas, Reis, Celso A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861914/ https://www.ncbi.nlm.nih.gov/pubmed/27161092 http://dx.doi.org/10.1038/srep25575 |
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