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Blast shockwaves propagate Ca(2+) activity via purinergic astrocyte networks in human central nervous system cells

In a recent study of the pathophysiology of mild, blast-induced traumatic brain injury (bTBI) the exposure of dissociated, central nervous system (CNS) cells to simulated blast resulted in propagating waves of elevated intracellular Ca(2+). Here we show, in dissociated human CNS cultures, that these...

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Detalles Bibliográficos
Autores principales: Ravin, Rea, Blank, Paul S., Busse, Brad, Ravin, Nitay, Vira, Shaleen, Bezrukov, Ludmila, Waters, Hang, Guerrero-Cazares, Hugo, Quinones-Hinojosa, Alfredo, Lee, Philip R., Fields, R. Douglas, Bezrukov, Sergey M., Zimmerberg, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861979/
https://www.ncbi.nlm.nih.gov/pubmed/27162174
http://dx.doi.org/10.1038/srep25713