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Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex
The purpose of this study was to determine whether exposure to specific auditory sequences leads to the induction of new motor memories and to investigate the role of the dorsal premotor cortex (dPMC) in this crossmodal learning process. Fifty-two young healthy non-musicians were familiarized with t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862034/ https://www.ncbi.nlm.nih.gov/pubmed/27242414 http://dx.doi.org/10.3389/fnins.2016.00210 |
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author | Stephan, Marianne A. Brown, Rachel Lega, Carlotta Penhune, Virginia |
author_facet | Stephan, Marianne A. Brown, Rachel Lega, Carlotta Penhune, Virginia |
author_sort | Stephan, Marianne A. |
collection | PubMed |
description | The purpose of this study was to determine whether exposure to specific auditory sequences leads to the induction of new motor memories and to investigate the role of the dorsal premotor cortex (dPMC) in this crossmodal learning process. Fifty-two young healthy non-musicians were familiarized with the sound to key-press mapping on a computer keyboard and tested on their baseline motor performance. Each participant received subsequently either continuous theta burst stimulation (cTBS) or sham stimulation over the dPMC and was then asked to remember a 12-note melody without moving. For half of the participants, the contour of the melody memorized was congruent to a subsequently performed, but never practiced, finger movement sequence (Congruent group). For the other half, the melody memorized was incongruent to the subsequent finger movement sequence (Incongruent group). Hearing a congruent melody led to significantly faster performance of a motor sequence immediately thereafter compared to hearing an incongruent melody. In addition, cTBS speeded up motor performance in both groups, possibly by relieving motor consolidation from interference by the declarative melody memorization task. Our findings substantiate recent evidence that exposure to a movement-related tone sequence can induce specific, crossmodal encoding of a movement sequence representation. They further suggest that cTBS over the dPMC may enhance early offline procedural motor skill consolidation in cognitive states where motor consolidation would normally be disturbed by concurrent declarative memory processes. These findings may contribute to a better understanding of auditory-motor system interactions and have implications for the development of new motor rehabilitation approaches using sound and non-invasive brain stimulation as neuromodulatory tools. |
format | Online Article Text |
id | pubmed-4862034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48620342016-05-30 Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex Stephan, Marianne A. Brown, Rachel Lega, Carlotta Penhune, Virginia Front Neurosci Psychology The purpose of this study was to determine whether exposure to specific auditory sequences leads to the induction of new motor memories and to investigate the role of the dorsal premotor cortex (dPMC) in this crossmodal learning process. Fifty-two young healthy non-musicians were familiarized with the sound to key-press mapping on a computer keyboard and tested on their baseline motor performance. Each participant received subsequently either continuous theta burst stimulation (cTBS) or sham stimulation over the dPMC and was then asked to remember a 12-note melody without moving. For half of the participants, the contour of the melody memorized was congruent to a subsequently performed, but never practiced, finger movement sequence (Congruent group). For the other half, the melody memorized was incongruent to the subsequent finger movement sequence (Incongruent group). Hearing a congruent melody led to significantly faster performance of a motor sequence immediately thereafter compared to hearing an incongruent melody. In addition, cTBS speeded up motor performance in both groups, possibly by relieving motor consolidation from interference by the declarative melody memorization task. Our findings substantiate recent evidence that exposure to a movement-related tone sequence can induce specific, crossmodal encoding of a movement sequence representation. They further suggest that cTBS over the dPMC may enhance early offline procedural motor skill consolidation in cognitive states where motor consolidation would normally be disturbed by concurrent declarative memory processes. These findings may contribute to a better understanding of auditory-motor system interactions and have implications for the development of new motor rehabilitation approaches using sound and non-invasive brain stimulation as neuromodulatory tools. Frontiers Media S.A. 2016-05-10 /pmc/articles/PMC4862034/ /pubmed/27242414 http://dx.doi.org/10.3389/fnins.2016.00210 Text en Copyright © 2016 Stephan, Brown, Lega and Penhune. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychology Stephan, Marianne A. Brown, Rachel Lega, Carlotta Penhune, Virginia Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title | Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title_full | Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title_fullStr | Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title_full_unstemmed | Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title_short | Melodic Priming of Motor Sequence Performance: The Role of the Dorsal Premotor Cortex |
title_sort | melodic priming of motor sequence performance: the role of the dorsal premotor cortex |
topic | Psychology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862034/ https://www.ncbi.nlm.nih.gov/pubmed/27242414 http://dx.doi.org/10.3389/fnins.2016.00210 |
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