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Stopping guidelines for an effectiveness trial: what should the protocol specify?

BACKGROUND: Despite long-standing problems in decisions to stop clinical trials, stopping guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assist the data monitoring committees for effectiveness trials. MAIN TEXT: To specif...

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Detalles Bibliográficos
Autores principales:	Tyson, Jon E., Pedroza, Claudia, Wallace, Dennis, D’Angio, Carl, Bell, Edward F., Das, Abhik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862046/ https://www.ncbi.nlm.nih.gov/pubmed/27165260 http://dx.doi.org/10.1186/s13063-016-1367-4

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