Cargando…

Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer

BACKGROUND: Podocalyxin-like 1 (PODXL) is an anti-adhesive transmembrane protein that has been demonstrated to be an independent factor of poor prognosis in colorectal cancer (CRC). The gene encoding PODXL is located to chromosome 7, which also harbours the gene for the epidermal growth factor recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Larsson, Anna H., Lehn, Sophie, Wangefjord, Sakarias, Karnevi, Emelie, Kuteeva, Eugenia, Sundström, Magnus, Nodin, Björn, Uhlén, Mathias, Eberhard, Jakob, Birgisson, Helgi, Jirström, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862047/ https://www.ncbi.nlm.nih.gov/pubmed/27160084 http://dx.doi.org/10.1186/s12967-016-0882-0

Ejemplares similares

Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer
por: Larsson, Anna, et al.
Publicado: (2012)

Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas
por: Heby, Margareta, et al.
Publicado: (2020)

Associations of Anthropometric Factors with KRAS and BRAF Mutation Status of Primary Colorectal Cancer in Men and Women: A Cohort Study
por: Brändstedt, Jenny, et al.
Publicado: (2014)

Podocalyxin-like protein expression in primary colorectal cancer and synchronous lymph node metastases
por: Larsson, Anna H, et al.
Publicado: (2013)

Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome
por: Bengtsson, Erik, et al.
Publicado: (2014)

Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer
por: Boman, K, et al.
Publicado: (2013)

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1 and 3 in Gastric and Esophageal Adenocarcinoma
por: Hedner, Charlotta, et al.
Publicado: (2016)

Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer
por: Larsson, A, et al.
Publicado: (2011)

Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer
por: Nodin, Björn, et al.
Publicado: (2012)

Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study
por: Wangefjord, Sakarias, et al.
Publicado: (2011)

Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability
por: Brändstedt, Jenny, et al.
Publicado: (2014)

Associations of beta-catenin alterations and MSI screening status with expression of key cell cycle regulating proteins and survival from colorectal cancer
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

Prognostic and predictive significance of podocalyxin-like protein expression in pancreatic and periampullary adenocarcinoma
por: Heby, Margareta, et al.
Publicado: (2015)

Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study
por: Brändstedt, Jenny, et al.
Publicado: (2013)

Expression of podocalyxin-like protein is an independent prognostic biomarker in resected esophageal and gastric adenocarcinoma
por: Borg, David, et al.
Publicado: (2016)

SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma
por: Hedner, Charlotta, et al.
Publicado: (2014)

Gender, anthropometric factors and risk of colorectal cancer with particular reference to tumour location and TNM stage: a cohort study
por: Brändstedt, Jenny, et al.
Publicado: (2012)

Translational study reveals a two-faced role of RBM3 in pancreatic cancer and suggests its potential value as a biomarker for improved patient stratification
por: Karnevi, Emelie, et al.
Publicado: (2017)

Podocalyxin-like protein as a predictive biomarker for benefit of neoadjuvant chemotherapy in resectable gastric and esophageal adenocarcinoma
por: Borg, David, et al.
Publicado: (2018)

The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype
por: Lundgren, Sebastian, et al.
Publicado: (2017)

A cohort study of the prognostic and treatment predictive value of SATB2 expression in colorectal cancer
por: Eberhard, J, et al.
Publicado: (2012)

Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study
por: Boman, Karolina, et al.
Publicado: (2017)

Expression and prognostic significance of the polymeric immunoglobulin receptor in esophageal and gastric adenocarcinoma
por: Fristedt, Richard, et al.
Publicado: (2014)

Chemotherapy, host response and molecular dynamics in periampullary cancer: the CHAMP study
por: Hau, Sofie Olsson, et al.
Publicado: (2020)

Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity
por: Wahlin, Sara, et al.
Publicado: (2022)

Mutational Landscape in Resected Periampullary Adenocarcinoma: Relationship With Morphology and Clinical Outcome
por: Lundgren, Sebastian, et al.
Publicado: (2019)

PRR11 unveiled as a top candidate biomarker within the RBM3‐regulated transcriptome in pancreatic cancer
por: Olsson Hau, Sofie, et al.
Publicado: (2021)

Low RBM3 Protein Expression Correlates with Clinical Stage, Prognostic Classification and Increased Risk of Treatment Failure in Testicular Non-Seminomatous Germ Cell Cancer
por: Olofsson, Sven-Erik, et al.
Publicado: (2015)

High expression of RNA-binding motif protein 3 in esophageal and gastric adenocarcinoma correlates with intestinal metaplasia-associated tumours and independently predicts a reduced risk of recurrence and death
por: Jonsson, Liv, et al.
Publicado: (2014)

Expression and Prognostic Significance of Human Epidermal Growth Factor Receptors 1, 2 and 3 in Periampullary Adenocarcinoma
por: Elebro, Jacob, et al.
Publicado: (2016)

Discovery of dachshund 2 protein as a novel biomarker of poor prognosis in epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2012)

Expression of the global regulator SATB1 is an independent factor of poor prognosis in high grade epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2012)

Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients
por: Gaber, Alexander, et al.
Publicado: (2010)

Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2013)

Prognostic and treatment predictive significance of SATB1 and SATB2 expression in pancreatic and periampullary adenocarcinoma
por: Elebro, Jacob, et al.
Publicado: (2014)

Reduced Expression of the Polymeric Immunoglobulin Receptor in Pancreatic and Periampullary Adenocarcinoma Signifies Tumour Progression and Poor Prognosis
por: Fristedt, Richard, et al.
Publicado: (2014)

Expression of programmed cell death protein 1 (PD-1) and its ligand PD-L1 in colorectal cancer: Relationship with sidedness and prognosis
por: Berntsson, Jonna, et al.
Publicado: (2018)

Pre-diagnostic anthropometry, sex, and risk of colorectal cancer according to tumor immune cell composition
por: Berntsson, Jonna, et al.
Publicado: (2019)

High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanoma
por: Nodin, Björn, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jnddlf0psapu27pkef5heeor6m