Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

BACKGROUND: Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Oxidative damage of mitochondria and cellular prote...

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Detalles Bibliográficos
Autores principales: De Filippis, Lidia, Halikere, Apoorva, McGowan, Heather, Moore, Jennifer C., Tischfield, Jay A., Hart, Ronald P., Pang, Zhiping P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862119/
https://www.ncbi.nlm.nih.gov/pubmed/27160314
http://dx.doi.org/10.1186/s13041-016-0221-7

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