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Next-generation sequencing-based detection of germline L1-mediated transductions
BACKGROUND: While active LINE-1 (L1) elements possess the ability to mobilize flanking sequences to different genomic loci through a process termed transduction influencing genomic content and structure, an approach for detecting polymorphic germline non-reference transductions in massively-parallel...
Autores principales: | Tica, Jelena, Lee, Eunjung, Untergasser, Andreas, Meiers, Sascha, Garfield, David A., Gokcumen, Omer, Furlong, Eileen E.M., Park, Peter J., Stütz, Adrian M., Korbel, Jan O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862182/ https://www.ncbi.nlm.nih.gov/pubmed/27161561 http://dx.doi.org/10.1186/s12864-016-2670-x |
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