rAAV-compatible MiniPromoters for restricted expression in the brain and eye

BACKGROUND: Small promoters that recapitulate endogenous gene expression patterns are important for basic, preclinical, and now clinical research. Recently, there has been a promising revival of gene therapy for diseases with unmet therapeutic needs. To date, most gene therapies have used viral-base...

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Detalles Bibliográficos
Autores principales: de Leeuw, Charles N., Korecki, Andrea J., Berry, Garrett E., Hickmott, Jack W., Lam, Siu Ling, Lengyell, Tess C., Bonaguro, Russell J., Borretta, Lisa J., Chopra, Vikramjit, Chou, Alice Y., D’Souza, Cletus A., Kaspieva, Olga, Laprise, Stéphanie, McInerny, Simone C., Portales-Casamar, Elodie, Swanson-Newman, Magdalena I., Wong, Kaelan, Yang, George S., Zhou, Michelle, Jones, Steven J. M., Holt, Robert A., Asokan, Aravind, Goldowitz, Daniel, Wasserman, Wyeth W., Simpson, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862195/
https://www.ncbi.nlm.nih.gov/pubmed/27164903
http://dx.doi.org/10.1186/s13041-016-0232-4

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