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Both tumour cells and infiltrating T-cells in equine sarcoids express FOXP3 associated with an immune-supressed cytokine microenvironment

Bovine papillomavirus (BPV) infections of equine species have a central role in the aetiology of equine sarcoids; a common benign skin tumour of horses, zebras and donkeys. Within the lesions, all of the early papillomavirus genes are expressed and promote the excessive replication of fibroblasts wh...

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Detalles Bibliográficos
Autores principales: Wilson, A. Douglas, Hicks, Chelsea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862206/
https://www.ncbi.nlm.nih.gov/pubmed/27160146
http://dx.doi.org/10.1186/s13567-016-0339-8