Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm

INTRODUCTION: Enlargement of a pre-existing intracranial aneurysm is a well-established risk factor of rupture. Excessive low wall shear stress concomitant with turbulent flow in the dome of an aneurysm may contribute to progression and rupture. However, how stress conditions regulate enlargement of...

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Detalles Bibliográficos
Autores principales: Aoki, Tomohiro, Yamamoto, Kimiko, Fukuda, Miyuki, Shimogonya, Yuji, Fukuda, Shunichi, Narumiya, Shuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862234/
https://www.ncbi.nlm.nih.gov/pubmed/27160403
http://dx.doi.org/10.1186/s40478-016-0318-3

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