Cargando…
TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum
Procollagens, pre-chylomicrons, and pre–very low-density lipoproteins (pre-VLDLs) are too big to fit into conventional COPII-coated vesicles, so how are these bulky cargoes exported from the endoplasmic reticulum (ER)? We have shown that TANGO1 located at the ER exit site is necessary for procollage...
Autores principales: | Santos, António J.M., Nogueira, Cristina, Ortega-Bellido, Maria, Malhotra, Vivek |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862334/ https://www.ncbi.nlm.nih.gov/pubmed/27138255 http://dx.doi.org/10.1083/jcb.201603072 |
Ejemplares similares
-
Dual function of cTAGE5 in collagen export from the endoplasmic reticulum
por: Tanabe, Tomoya, et al.
Publicado: (2016) -
cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites
por: Saito, Kota, et al.
Publicado: (2011) -
Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export
por: Saito, Kota, et al.
Publicado: (2014) -
TANGO1 recruits ERGIC membranes to the endoplasmic reticulum for procollagen export
por: Santos, António JM, et al.
Publicado: (2015) -
A physical mechanism of TANGO1-mediated bulky cargo export
por: Raote, Ishier, et al.
Publicado: (2020)