Rab-mediated membrane trafficking and the control of epithelial cell polarity

Development of cell polarity requires apical trafficking of podocalyxin; yet the regulation of its transport is unclear. In this issue, Mrozowska and Fukuda (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512024) demonstrate that different sets of Rabs and Rab effectors are used to regulate po...

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Detalles Bibliográficos
Autores principales: Ioannou, Maria S., McPherson, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862336/
https://www.ncbi.nlm.nih.gov/pubmed/27138254
http://dx.doi.org/10.1083/jcb.201604076
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author Ioannou, Maria S.
McPherson, Peter S.
author_facet Ioannou, Maria S.
McPherson, Peter S.
author_sort Ioannou, Maria S.
collection PubMed
description Development of cell polarity requires apical trafficking of podocalyxin; yet the regulation of its transport is unclear. In this issue, Mrozowska and Fukuda (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512024) demonstrate that different sets of Rabs and Rab effectors are used to regulate podocalyxin trafficking in two- versus three-dimensional model systems.
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spelling pubmed-48623362016-11-09 Rab-mediated membrane trafficking and the control of epithelial cell polarity Ioannou, Maria S. McPherson, Peter S. J Cell Biol Commentary Development of cell polarity requires apical trafficking of podocalyxin; yet the regulation of its transport is unclear. In this issue, Mrozowska and Fukuda (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512024) demonstrate that different sets of Rabs and Rab effectors are used to regulate podocalyxin trafficking in two- versus three-dimensional model systems. The Rockefeller University Press 2016-05-09 /pmc/articles/PMC4862336/ /pubmed/27138254 http://dx.doi.org/10.1083/jcb.201604076 Text en © 2016 Ioannou and McPherson This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Ioannou, Maria S.
McPherson, Peter S.
Rab-mediated membrane trafficking and the control of epithelial cell polarity
title Rab-mediated membrane trafficking and the control of epithelial cell polarity
title_full Rab-mediated membrane trafficking and the control of epithelial cell polarity
title_fullStr Rab-mediated membrane trafficking and the control of epithelial cell polarity
title_full_unstemmed Rab-mediated membrane trafficking and the control of epithelial cell polarity
title_short Rab-mediated membrane trafficking and the control of epithelial cell polarity
title_sort rab-mediated membrane trafficking and the control of epithelial cell polarity
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862336/
https://www.ncbi.nlm.nih.gov/pubmed/27138254
http://dx.doi.org/10.1083/jcb.201604076
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