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Spirolactone provides protection from renal fibrosis by inhibiting the endothelial–mesenchymal transition in isoprenaline-induced heart failure in rats

BACKGROUND: Fibrosis results in excessive accumulation of extracellular matrix proteins, collagen component alteration, and abnormalities in structure and is partly derived from a process called the endothelial–mesenchymal transition involving transforming growth factor β (TGF-β). We investigated wh...

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Detalles Bibliográficos
Autores principales:	Zhou, Hao, Xi, Dan, Liu, Jichen, Zhao, Jinjin, Chen, Si, Guo, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862356/ https://www.ncbi.nlm.nih.gov/pubmed/27217725 http://dx.doi.org/10.2147/DDDT.S100095

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