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Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making it an attract...

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Detalles Bibliográficos
Autores principales: Lin, Kun-Yuan, Cheng, Siao Muk, Tsai, Shing-Ling, Tsai, Ju-Ya, Lin, Chun-Hui, Cheung, Chun Hei Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862386/
https://www.ncbi.nlm.nih.gov/pubmed/27217778
http://dx.doi.org/10.2147/OTT.S101209