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Uracil-induced signaling pathways for DUOX-dependent gut immunity

Intestinal dual oxidase (DUOX) activation is the first line of host defense against enteric infection in Drosophila. DUOX enzymatic activity is mainly controlled by phospholipase C-β (PLCβ)-dependent calcium mobilization, whereas DUOX gene expression is mainly controlled by the MEKK1-p38 mitogen-act...

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Detalles Bibliográficos
Autores principales:	Lee, Kyung-Ah, Kim, Boram, You, Hyejin, Lee, Won-Jae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Extra View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862428/ https://www.ncbi.nlm.nih.gov/pubmed/26655037 http://dx.doi.org/10.1080/19336934.2015.1126011

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