Enhancement of the Replication of Hepatitis C Virus Replicons of Genotypes 1 to 4 by Manipulation of CpG and UpA Dinucleotide Frequencies and Use of Cell Lines Expressing SECL14L2 for Antiviral Resistance Testing

Treatment for hepatitis C virus (HCV) has improved greatly through the use of direct-acting antivirals (DAAs). However, their effectiveness and potential for drug resistance development in non-genotype 1 variants of HCV remain relatively unexplored, as in vitro assays to assess drug susceptibility a...

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Detalles Bibliográficos
Autores principales: Witteveldt, Jeroen, Martin-Gans, Marion, Simmonds, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Analytical Procedures
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862521/
https://www.ncbi.nlm.nih.gov/pubmed/26953209
http://dx.doi.org/10.1128/AAC.02932-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862521/
https://www.ncbi.nlm.nih.gov/pubmed/26953209
http://dx.doi.org/10.1128/AAC.02932-15

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