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Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission

The majority of new Human Immunodeficiency Virus (HIV)-1 infections are acquired via sexual transmission at mucosal surfaces. Partial efficacy (31.2%) of the Thai RV144 HIV-1 vaccine trial has been correlated with Antibody-dependent Cellular Cytotoxicity (ADCC) mediated by non-neutralizing antibodie...

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Detalles Bibliográficos
Autores principales: Cheeseman, Hannah M., Carias, Ann M., Evans, Abbey B., Olejniczak, Natalia J., Ziprin, Paul, King, Deborah F. L., Hope, Thomas J., Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862624/
https://www.ncbi.nlm.nih.gov/pubmed/27164006
http://dx.doi.org/10.1371/journal.pone.0154656