Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus

Due to the stringent population bottleneck that occurs during sexual HIV-1 transmission, systemic infection is typically established by a limited number of founder viruses. Elucidation of the precise forces influencing the selection of founder viruses may reveal key vulnerabilities that could aid in...

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Detalles Bibliográficos
Autores principales: Tully, Damien C., Ogilvie, Colin B., Batorsky, Rebecca E., Bean, David J., Power, Karen A., Ghebremichael, Musie, Bedard, Hunter E., Gladden, Adrianne D., Seese, Aaron M., Amero, Molly A., Lane, Kimberly, McGrath, Graham, Bazner, Suzane B., Tinsley, Jake, Lennon, Niall J., Henn, Matthew R., Brumme, Zabrina L., Norris, Philip J., Rosenberg, Eric S., Mayer, Kenneth H., Jessen, Heiko, Kosakovsky Pond, Sergei L., Walker, Bruce D., Altfeld, Marcus, Carlson, Jonathan M., Allen, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862634/
https://www.ncbi.nlm.nih.gov/pubmed/27163788
http://dx.doi.org/10.1371/journal.ppat.1005619

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