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Structural Determinants of Misfolding in Multidomain Proteins

Recent single molecule experiments, using either atomic force microscopy (AFM) or Förster resonance energy transfer (FRET) have shown that multidomain proteins containing tandem repeats may form stable misfolded structures. Topology-based simulation models have been used successfully to generate mod...

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Detalles Bibliográficos
Autores principales:	Tian, Pengfei, Best, Robert B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862688/ https://www.ncbi.nlm.nih.gov/pubmed/27163669 http://dx.doi.org/10.1371/journal.pcbi.1004933

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