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Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas

Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency...

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Autores principales: Garba, Abdoul Aziz, Adamou, Harissou, Magagi, Ibrahim Amadou, Brah, Souleymane, Habou, Oumarou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862778/
https://www.ncbi.nlm.nih.gov/pubmed/27217874
http://dx.doi.org/10.11604/pamj.2016.23.48.8909
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author Garba, Abdoul Aziz
Adamou, Harissou
Magagi, Ibrahim Amadou
Brah, Souleymane
Habou, Oumarou
author_facet Garba, Abdoul Aziz
Adamou, Harissou
Magagi, Ibrahim Amadou
Brah, Souleymane
Habou, Oumarou
author_sort Garba, Abdoul Aziz
collection PubMed
description Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency with acute intestinal obstruction. During the surgery, we found a tumor on the small intestine with mesenteric lymphadenopathy. Histology and immunohistochemistry of the specimen objectified a digestive T lymphoma CD3+ and immunological assessment of celiac disease was positive. The diagnosis of EATL was thus retained. Chemotherapy (CHOEP protocol) was established as well as gluten-free diet with a complete response to treatment. The EATL is a rare complication of CD that can be revealed by intestinal obstruction. The prognosis can be improved by early treatment involving surgery and chemotherapy. Its prevention requires early diagnosis of celiac and gluten-free diets.
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spelling pubmed-48627782016-05-23 Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas Garba, Abdoul Aziz Adamou, Harissou Magagi, Ibrahim Amadou Brah, Souleymane Habou, Oumarou Pan Afr Med J Case Report Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency with acute intestinal obstruction. During the surgery, we found a tumor on the small intestine with mesenteric lymphadenopathy. Histology and immunohistochemistry of the specimen objectified a digestive T lymphoma CD3+ and immunological assessment of celiac disease was positive. The diagnosis of EATL was thus retained. Chemotherapy (CHOEP protocol) was established as well as gluten-free diet with a complete response to treatment. The EATL is a rare complication of CD that can be revealed by intestinal obstruction. The prognosis can be improved by early treatment involving surgery and chemotherapy. Its prevention requires early diagnosis of celiac and gluten-free diets. The African Field Epidemiology Network 2016-02-19 /pmc/articles/PMC4862778/ /pubmed/27217874 http://dx.doi.org/10.11604/pamj.2016.23.48.8909 Text en © Abdoul Aziz Garba et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Garba, Abdoul Aziz
Adamou, Harissou
Magagi, Ibrahim Amadou
Brah, Souleymane
Habou, Oumarou
Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title_full Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title_fullStr Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title_full_unstemmed Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title_short Occlusion intestinale aigue révélant un lymphome T digestif associé à la maladie cœliaque, à propos d'un cas
title_sort occlusion intestinale aigue révélant un lymphome t digestif associé à la maladie cœliaque, à propos d'un cas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862778/
https://www.ncbi.nlm.nih.gov/pubmed/27217874
http://dx.doi.org/10.11604/pamj.2016.23.48.8909
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