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Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas
Peutz-Jeghers syndrome (SPJ) is characterized by intestinal hamartomatous polyps in association with mucocutaneous lentiginosis. Patients are exposed to mechanical and bleeding complications. It is a cancer predisposition syndrome. Our study highlights the diagnostic criteria for Peutz-Jeghers syndr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862783/ https://www.ncbi.nlm.nih.gov/pubmed/27217901 http://dx.doi.org/10.11604/pamj.2016.23.78.8862 |
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author | Martinetti, Andrianimaro Florelia Andriantsoa, Rasoanaivo Mamy Andriambelo, Rajaonera Tovohery Nicole, Rakotoarison Ratsaraharimanana Cathérine Enintsoa, Raveloson Nasolotsiry |
author_facet | Martinetti, Andrianimaro Florelia Andriantsoa, Rasoanaivo Mamy Andriambelo, Rajaonera Tovohery Nicole, Rakotoarison Ratsaraharimanana Cathérine Enintsoa, Raveloson Nasolotsiry |
author_sort | Martinetti, Andrianimaro Florelia |
collection | PubMed |
description | Peutz-Jeghers syndrome (SPJ) is characterized by intestinal hamartomatous polyps in association with mucocutaneous lentiginosis. Patients are exposed to mechanical and bleeding complications. It is a cancer predisposition syndrome. Our study highlights the diagnostic criteria for Peutz-Jeghers syndrome (SPJ), the complications and the therapeutic progresses in patient care. We report the case of a 32-year-old male presenting with a massive melaena. It was hospitalized in the surgical intensive care unit with hypovolemic shock difficult to control. This required surgical intervention to stop bleeding. We found a hamartomatous polyps in the small intestine which caused bleeding. Peutz Jeghers Syndrome was diagnosed on the basis of labial lentigines during childhood. Clinical and paraclinical explorations did not reveal the presence of cancer. In Madagascar, this disease is still poorly understood. In the literature, the diagnosis of Peutz Jeghers syndrome is based on clinical findings or on the presence of complications such as haemorrhage, invagination or bowel obstruction. In our case, the disease was complicated by gastrointestinal bleeding with hypovolemic shock. Endoscopic polypectomy using double-balloon enteroscopy can reduce emergency small bowel surgery. Peutz-Jeghers syndrome is a rare disease. Despite this, it is important for clinicians to know it and to take it into consideration in case of gastrointestinal bleeding. |
format | Online Article Text |
id | pubmed-4862783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-48627832016-05-23 Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas Martinetti, Andrianimaro Florelia Andriantsoa, Rasoanaivo Mamy Andriambelo, Rajaonera Tovohery Nicole, Rakotoarison Ratsaraharimanana Cathérine Enintsoa, Raveloson Nasolotsiry Pan Afr Med J Case Report Peutz-Jeghers syndrome (SPJ) is characterized by intestinal hamartomatous polyps in association with mucocutaneous lentiginosis. Patients are exposed to mechanical and bleeding complications. It is a cancer predisposition syndrome. Our study highlights the diagnostic criteria for Peutz-Jeghers syndrome (SPJ), the complications and the therapeutic progresses in patient care. We report the case of a 32-year-old male presenting with a massive melaena. It was hospitalized in the surgical intensive care unit with hypovolemic shock difficult to control. This required surgical intervention to stop bleeding. We found a hamartomatous polyps in the small intestine which caused bleeding. Peutz Jeghers Syndrome was diagnosed on the basis of labial lentigines during childhood. Clinical and paraclinical explorations did not reveal the presence of cancer. In Madagascar, this disease is still poorly understood. In the literature, the diagnosis of Peutz Jeghers syndrome is based on clinical findings or on the presence of complications such as haemorrhage, invagination or bowel obstruction. In our case, the disease was complicated by gastrointestinal bleeding with hypovolemic shock. Endoscopic polypectomy using double-balloon enteroscopy can reduce emergency small bowel surgery. Peutz-Jeghers syndrome is a rare disease. Despite this, it is important for clinicians to know it and to take it into consideration in case of gastrointestinal bleeding. The African Field Epidemiology Network 2016-03-10 /pmc/articles/PMC4862783/ /pubmed/27217901 http://dx.doi.org/10.11604/pamj.2016.23.78.8862 Text en © Andrianimaro Florelia Martinetti et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Martinetti, Andrianimaro Florelia Andriantsoa, Rasoanaivo Mamy Andriambelo, Rajaonera Tovohery Nicole, Rakotoarison Ratsaraharimanana Cathérine Enintsoa, Raveloson Nasolotsiry Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title | Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title_full | Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title_fullStr | Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title_full_unstemmed | Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title_short | Melæna massif révélant un syndrome de Peutz-Jeghers vu au CHU-JRA Madagascar: à propos d'un cas |
title_sort | melæna massif révélant un syndrome de peutz-jeghers vu au chu-jra madagascar: à propos d'un cas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862783/ https://www.ncbi.nlm.nih.gov/pubmed/27217901 http://dx.doi.org/10.11604/pamj.2016.23.78.8862 |
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