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Fecal Microbiota Transplantation Inhibits Multidrug-Resistant Gut Pathogens: Preliminary Report Performed in an Immunocompromised Host

Colonization of the gastrointestinal tract with multidrug-resistant (MDR) bacteria is a consequence of gut dysbiosis. We describe the successful utilization of fecal microbiota transplantation to inhibit Klebsiella pneumoniae MBL(+) and Escherichia coli ESBL(+) gut colonization in the immunocompromi...

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Detalles Bibliográficos
Autores principales: Biliński, Jarosław, Grzesiowski, Paweł, Muszyński, Jacek, Wróblewska, Marta, Mądry, Krzysztof, Robak, Katarzyna, Dzieciątkowski, Tomasz, Wiktor-Jedrzejczak, Wiesław, Basak, Grzegorz W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863031/
https://www.ncbi.nlm.nih.gov/pubmed/26960790
http://dx.doi.org/10.1007/s00005-016-0387-9
Descripción
Sumario:Colonization of the gastrointestinal tract with multidrug-resistant (MDR) bacteria is a consequence of gut dysbiosis. We describe the successful utilization of fecal microbiota transplantation to inhibit Klebsiella pneumoniae MBL(+) and Escherichia coli ESBL(+) gut colonization in the immunocompromised host as a novel tool in the battle against MDR microorganisms. ClinicalTrials.gov identifier NCT02461199.