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Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System

Objective. To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS). Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked potentials and electroretinograms in conscious and a...

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Detalles Bibliográficos
Autores principales:	Charng, Jason, He, Zheng, Vingrys, Algis J., Fish, Rebecca L., Gurrell, Rachel, Bui, Bang V., Nguyen, Christine T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863103/ https://www.ncbi.nlm.nih.gov/pubmed/27239335 http://dx.doi.org/10.1155/2016/5801826

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