Neuropilin-1(high)CD4(+)CD25(+) Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4(+)CD25(+)Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1(high)CD4(+)CD25(+)Tregs and the potential therapeutic va...

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Detalles Bibliográficos
Autores principales: Gao, Yu-Lei, Chai, Yan-Fen, Qi, An-Long, Yao, Ying, Liu, Yan-Cun, Dong, Ning, Wang, Li-Jun, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863118/
https://www.ncbi.nlm.nih.gov/pubmed/27239104
http://dx.doi.org/10.1155/2016/7132158

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