Cargando…

TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients

Background: TP53 mutations are among the most common mutations found in lung cancers, identified as an independent prognostic factor in many types of cancers. The purpose of this study was to investigate the frequency and prognostic impact of TP53 mutations in never-smokers and in different histolog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Halvorsen, Ann R., Silwal-Pandit, Laxmi, Meza-Zepeda, Leonardo A., Vodak, Daniel, Vu, Phuong, Sagerup, Camilla, Hovig, Eivind, Myklebost, Ola, Børresen-Dale, Anne-Lise, Brustugun, Odd T., Helland, Åslaug
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863128/ https://www.ncbi.nlm.nih.gov/pubmed/27242894 http://dx.doi.org/10.3389/fgene.2016.00085

Ejemplares similares

High number of kinome‐mutations in non‐small cell lung cancer is associated with reduced immune response and poor relapse‐free survival
por: Helland, Å., et al.
Publicado: (2017)

Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
por: Namløs, Heidi M., et al.
Publicado: (2017)

Chromosomal instability and a deregulated cell cycle are intrinsic features of high‐risk gastrointestinal stromal tumours with a metastatic potential
por: Namløs, Heidi Maria, et al.
Publicado: (2023)

Genome‐wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
por: Bjaanæs, Maria Moksnes, et al.
Publicado: (2015)

GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
por: Lyng, Heidi, et al.
Publicado: (2008)

Performance comparison of four exome capture systems for deep sequencing
por: Chilamakuri, Chandra Sekhar Reddy, et al.
Publicado: (2014)

Sample-Index Misassignment Impacts Tumour Exome Sequencing
por: Vodák, Daniel, et al.
Publicado: (2018)

Prognostic Significance of the Loss of Heterozygosity of KRAS in Early-Stage Lung Adenocarcinoma
por: Khadse, Anand, et al.
Publicado: (2022)

Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
por: Haakensen, Vilde D., et al.
Publicado: (2020)

Whole genome copy number analyses reveal a highly aberrant genome in TP53 mutant lung adenocarcinoma tumors
por: Bjaanæs, Maria Moksnes, et al.
Publicado: (2021)

NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors
por: McGowan, Marc, et al.
Publicado: (2017)

Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses
por: Turzer, Martin, et al.
Publicado: (2010)

Personal Cancer Genome Reporter: variant interpretation report for precision oncology
por: Nakken, Sigve, et al.
Publicado: (2018)

PathTracer: High-sensitivity detection of differential pathway activity in tumours
por: Nygård, Ståle, et al.
Publicado: (2019)

Stereotactic Body Radiation Therapy Is Effective and Safe in Patients with Early-Stage Non-Small Cell Lung Cancer with Low Performance Status and Severe Comorbidity
por: Turzer, Martin, et al.
Publicado: (2011)

Novel Molecular Tumor Cell Markers in Regional Lymph Nodes and Blood Samples from Patients Undergoing Surgery for Non-Small Cell Lung Cancer
por: Nordgård, Oddmund, et al.
Publicado: (2013)

Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC
por: Halvorsen, Ann Rita, et al.
Publicado: (2019)

Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
por: Bjaanæs, Maria Moksnes, et al.
Publicado: (2014)

NUT expression in primary lung tumours
por: Lund-Iversen, Marius, et al.
Publicado: (2015)

The immune microenvironment in non‐small cell lung cancer is predictive of prognosis after surgery
por: Öjlert, Åsa Kristina, et al.
Publicado: (2019)

Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers
por: Berg, Janna, et al.
Publicado: (2021)

Patterns of genomic evolution in advanced melanoma
por: Birkeland, E., et al.
Publicado: (2018)

Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
por: Berg, Janna, et al.
Publicado: (2018)

Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
por: Halvorsen, Ann Rita, et al.
Publicado: (2020)

The MYCN-HMGA2-CDKN2A pathway in non-small cell lung carcinoma—differences in histological subtypes
por: Eide, Hanne A., et al.
Publicado: (2016)

Tracheal cancer: a rare and deadly but potentially curable disease that also affects younger people
por: Nilssen, Yngvar, et al.
Publicado: (2023)

Osteopontin is a prognostic biomarker in non-small cell lung cancer
por: Rud, Ane Kongsgaard, et al.
Publicado: (2013)

Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data
por: Wang, Junbai, et al.
Publicado: (2003)

Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
por: Venizelos, Andreas, et al.
Publicado: (2022)

Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
por: Giliberto, Mariaserena, et al.
Publicado: (2022)

Limitations of mRNA amplification from small-size cell samples
por: Nygaard, Vigdis, et al.
Publicado: (2005)

Genetic differences between smokers and never-smokers with lung cancer
por: Kuśnierczyk, Piotr
Publicado: (2023)

Addiction to the nicotine gum in never smokers
por: Etter, Jean-François
Publicado: (2007)

Never-smoker African–American women suffer more from COPD compared with never-smoker Caucasian women
por: Sumon, Mahbubur, et al.
Publicado: (2020)

Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
por: Joly-Battaglini, Albane, et al.
Publicado: (2016)

The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
por: Frafjord, Astri, et al.
Publicado: (2021)

Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
por: Lyng, Heidi, et al.
Publicado: (2004)

Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
por: Eide, Hanne Astrid, et al.
Publicado: (2016)

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers
por: Faiz, Alen, et al.
Publicado: (2019)

Descriptive characteristics of hospitalized adult smokers and never-smokers with COVID-19
por: Kalan, Mohammad Ebrahimi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5d544f9l45kl0l0q2ghnncpknf