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An activation-induced IL-15 isoform is a natural antagonist for IL-15 function

Interleukin 15 (IL-15) expression induces the secretion of inflammatory cytokines, inhibits the apoptosis of activated T cells and prolongs the survival of CD8(+) memory T cells. Here we identified an IL-15 isoform lacking exon-6, IL-15ΔE6, generated by alternative splicing events of activated immun...

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Detalles Bibliográficos
Autores principales:	Zhao, Lei, Hu, Bo, Zhang, Yinsheng, Song, Yuan, Lin, Dandan, Liu, Yonghao, Mei, Yu, Sandikin, Dedy, Sun, Weiping, Zhuang, Min, Liu, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863161/ https://www.ncbi.nlm.nih.gov/pubmed/27166125 http://dx.doi.org/10.1038/srep25822

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