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The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery
Lipofectamine reagents are widely accepted as “gold-standard” for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell i...
Autores principales: | Cardarelli, Francesco, Digiacomo, Luca, Marchini, Cristina, Amici, Augusto, Salomone, Fabrizio, Fiume, Giuseppe, Rossetta, Alessandro, Gratton, Enrico, Pozzi, Daniela, Caracciolo, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863168/ https://www.ncbi.nlm.nih.gov/pubmed/27165510 http://dx.doi.org/10.1038/srep25879 |
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