Cargando…
IL-17A deficiency promotes periosteal bone formation in a model of inflammatory arthritis
BACKGROUND: Interleukin-17A (IL-17A) plays a pathogenic role in several rheumatic diseases including spondyloarthritis and, paradoxically, has been described to both promote and protect from bone formation. We therefore examined the effects of IL-17A on osteoblast differentiation in vitro and on per...
Autores principales: | Shaw, Anita T., Maeda, Yukiko, Gravallese, Ellen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863346/ https://www.ncbi.nlm.nih.gov/pubmed/27165410 http://dx.doi.org/10.1186/s13075-016-0998-x |
Ejemplares similares
-
Mechanisms of bone loss in inflammatory arthritis: diagnosis and therapeutic implications
por: Goldring, Steven R, et al.
Publicado: (2000) -
Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells
por: Shah, Mittal, et al.
Publicado: (2020) -
Histopathology of Bone Erosions in Rheumatoid Arthritis
por: Gravallese, Ellen, et al.
Publicado: (2000) -
Discovery of a periosteal stem cell mediating intramembranous bone formation
por: Debnath, Shawon, et al.
Publicado: (2018) -
Remodeling of Actin Cytoskeleton in Mouse Periosteal Cells under Mechanical Loading Induces Periosteal Cell Proliferation during Bone Formation
por: Sakai, Daisuke, et al.
Publicado: (2011)