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The pharmacology and therapeutic potential of (−)-huperzine A
(−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863551/ https://www.ncbi.nlm.nih.gov/pubmed/27186124 http://dx.doi.org/10.2147/JEP.S27084 |
| _version_ | 1782431498091102208 |
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| author | Tun, Maung Kyaw Moe Herzon, Seth B |
| author_facet | Tun, Maung Kyaw Moe Herzon, Seth B |
| author_sort | Tun, Maung Kyaw Moe |
| collection | PubMed |
| description | (−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic potential of (−)-huperzine A (1). Synthetic studies of (−)-huperzine A (1) aimed at enabling its development as a pharmaceutical will be described. |
| format | Online Article Text |
| id | pubmed-4863551 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Dove Medical Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-48635512016-05-16 The pharmacology and therapeutic potential of (−)-huperzine A Tun, Maung Kyaw Moe Herzon, Seth B J Exp Pharmacol Review (−)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer’s disease. In this review, we will discuss the pharmacology and therapeutic potential of (−)-huperzine A (1). Synthetic studies of (−)-huperzine A (1) aimed at enabling its development as a pharmaceutical will be described. Dove Medical Press 2012-09-05 /pmc/articles/PMC4863551/ /pubmed/27186124 http://dx.doi.org/10.2147/JEP.S27084 Text en © 2012 Tun and Herzon, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
| spellingShingle | Review Tun, Maung Kyaw Moe Herzon, Seth B The pharmacology and therapeutic potential of (−)-huperzine A |
| title | The pharmacology and therapeutic potential of (−)-huperzine A |
| title_full | The pharmacology and therapeutic potential of (−)-huperzine A |
| title_fullStr | The pharmacology and therapeutic potential of (−)-huperzine A |
| title_full_unstemmed | The pharmacology and therapeutic potential of (−)-huperzine A |
| title_short | The pharmacology and therapeutic potential of (−)-huperzine A |
| title_sort | pharmacology and therapeutic potential of (−)-huperzine a |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863551/ https://www.ncbi.nlm.nih.gov/pubmed/27186124 http://dx.doi.org/10.2147/JEP.S27084 |
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