Directed selection of influenza virus produces antigenic variants that match circulating human virus isolates and escape from vaccine‐mediated immune protection

Influenza vaccination does not provide 100% protection from infection, partly due to antigenic drift of the haemagglutinin (HA) protein. Low serum antibody titres increase the risk of infection. To determine whether there were additional correlates of risk, we examined the relationship between human...

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Detalles Bibliográficos
Autores principales: DeDiego, Marta L., Anderson, Christopher S., Yang, Hongmei, Holden‐Wiltse, Jeanne, Fitzgerald, Theresa, Treanor, John. J., Topham, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863573/
https://www.ncbi.nlm.nih.gov/pubmed/26854888
http://dx.doi.org/10.1111/imm.12594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863573/
https://www.ncbi.nlm.nih.gov/pubmed/26854888
http://dx.doi.org/10.1111/imm.12594

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