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Viral Determinants of miR-122-Independent Hepatitis C Virus Replication

Hepatitis C virus (HCV) replication requires binding of the liver-specific microRNA (miRNA) miR-122 to two sites in the HCV 5′ untranslated region (UTR). Although we and others have shown that viral genetics impact the amount of active miR-122 required for replication, it is unclear if HCV can repli...

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Detalles Bibliográficos
Autores principales: Hopcraft, Sharon E., Azarm, Kristopher D., Israelow, Benjamin, Lévêque, Nicolas, Schwarz, Megan C., Hsu, Tien-Huei, Chambers, Matthew T., Sourisseau, Marion, Semler, Bert L., Evans, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863629/
https://www.ncbi.nlm.nih.gov/pubmed/27303683
http://dx.doi.org/10.1128/mSphere.00009-15