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Viral Determinants of miR-122-Independent Hepatitis C Virus Replication
Hepatitis C virus (HCV) replication requires binding of the liver-specific microRNA (miRNA) miR-122 to two sites in the HCV 5′ untranslated region (UTR). Although we and others have shown that viral genetics impact the amount of active miR-122 required for replication, it is unclear if HCV can repli...
Autores principales: | Hopcraft, Sharon E., Azarm, Kristopher D., Israelow, Benjamin, Lévêque, Nicolas, Schwarz, Megan C., Hsu, Tien-Huei, Chambers, Matthew T., Sourisseau, Marion, Semler, Bert L., Evans, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863629/ https://www.ncbi.nlm.nih.gov/pubmed/27303683 http://dx.doi.org/10.1128/mSphere.00009-15 |
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