Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite Plasmodium falciparum

Plasmodium falciparum topoisomerase VIB (TopoVIB)-TopoVIA (TopoVIB-VIA) complex can be potentially exploited as a drug target against malaria due to its absence from the human genome. Previous work in our laboratory has suggested that P. falciparum TopoVIB (PfTopoVIB) might be a target of radicicol...

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Detalles Bibliográficos
Autores principales: Chalapareddy, Sureshkumar, Chakrabarty, Swati, Bhattacharyya, Mrinal Kanti, Bhattacharyya, Sunanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863635/
https://www.ncbi.nlm.nih.gov/pubmed/27303712
http://dx.doi.org/10.1128/mSphere.00025-15

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