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A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform

Recombinant adeno-associated vectors based on serotype 9 (rAAV9) have demonstrated highly effective gene transfer in multiple animal models of muscular dystrophies and other neurological indications. Current limitations in vector production and purification have hampered widespread implementation of...

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Detalles Bibliográficos
Autores principales:	Adamson-Small, Laura, Potter, Mark, Falk, Darin J, Cleaver, Brian, Byrne, Barry J, Clément, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863725/ https://www.ncbi.nlm.nih.gov/pubmed/27222839 http://dx.doi.org/10.1038/mtm.2016.31

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