Cargando…

Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

The tumor stroma is no longer seen solely as physical support for mutated epithelial cells but as an important modulator and even a driver of tumorigenicity. Within the tumor stromal milieu, heterogeneous populations of fibroblast-like cells, collectively termed carcinoma-associated fibroblasts (CAF...

Descripción completa

Detalles Bibliográficos
Autores principales: Gascard, Philippe, Tlsty, Thea D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863733/
https://www.ncbi.nlm.nih.gov/pubmed/27151975
http://dx.doi.org/10.1101/gad.279737.116