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Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
The tumor stroma is no longer seen solely as physical support for mutated epithelial cells but as an important modulator and even a driver of tumorigenicity. Within the tumor stromal milieu, heterogeneous populations of fibroblast-like cells, collectively termed carcinoma-associated fibroblasts (CAF...
Autores principales: | Gascard, Philippe, Tlsty, Thea D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863733/ https://www.ncbi.nlm.nih.gov/pubmed/27151975 http://dx.doi.org/10.1101/gad.279737.116 |
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