Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution

Motor axons approach muscles that are prepatterned in the prospective synaptic region. In mice, prepatterning of acetylcholine receptors requires Lrp4, a LDLR family member, and MuSK, a receptor tyrosine kinase. Lrp4 can bind and stimulate MuSK, strongly suggesting that association between Lrp4 and...

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Detalles Bibliográficos
Autores principales: Remédio, Leonor, Gribble, Katherine D., Lee, Jennifer K., Kim, Natalie, Hallock, Peter T., Delestrée, Nicolas, Mentis, George Z., Froemke, Robert C., Granato, Michael, Burden, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863737/
https://www.ncbi.nlm.nih.gov/pubmed/27151977
http://dx.doi.org/10.1101/gad.279745.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863737/
https://www.ncbi.nlm.nih.gov/pubmed/27151977
http://dx.doi.org/10.1101/gad.279745.116

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