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Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis
Genomic analyses of the myeloid malignancies and clonal disorders of hematopoiesis that may give rise to these disorders have identified that mutations in genes encoding core spliceosomal proteins and accessory regulatory splicing factors are among the most common targets of somatic mutations. These...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863743/ https://www.ncbi.nlm.nih.gov/pubmed/27151974 http://dx.doi.org/10.1101/gad.278424.116 |