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A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report

Patients with systemic lupus erythematosus (SLE) are susceptible to tuberculosis (TB), especially in endemic areas such as China. The variable and nonspecific clinical features of disseminated TB often leads to an erroneous or misdiagnosis. When a patient presents with TB of the bone marrow, the cli...

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Autores principales: Chen, Dongying, Yang, Zheng, Yang, Ying, Zhan, Zhongping, Yang, Xiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863787/
https://www.ncbi.nlm.nih.gov/pubmed/27149470
http://dx.doi.org/10.1097/MD.0000000000003552
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author Chen, Dongying
Yang, Zheng
Yang, Ying
Zhan, Zhongping
Yang, Xiuyan
author_facet Chen, Dongying
Yang, Zheng
Yang, Ying
Zhan, Zhongping
Yang, Xiuyan
author_sort Chen, Dongying
collection PubMed
description Patients with systemic lupus erythematosus (SLE) are susceptible to tuberculosis (TB), especially in endemic areas such as China. The variable and nonspecific clinical features of disseminated TB often leads to an erroneous or misdiagnosis. When a patient presents with TB of the bone marrow, the clinical condition is more perplexing and the prognosis is typically poor. Till now, there is no case report after apatinib came in the market. Here, we report a case of TB of the bone marrow accompanied with SLE. The patient exhibited remarkable features, including widespread lesions in the lungs, spinal vertebrae, sacrum, and ilium that were found to be consistent with TB of the bone marrow after histopathological examination. This case highlights the importance of clinical suspicion for TB during the follow-up of SLE patients, especially in endemic areas. An aggressive diagnostic biopsy should be performed in suspected TB patients as early as possible.
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spelling pubmed-48637872016-06-01 A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report Chen, Dongying Yang, Zheng Yang, Ying Zhan, Zhongping Yang, Xiuyan Medicine (Baltimore) 6900 Patients with systemic lupus erythematosus (SLE) are susceptible to tuberculosis (TB), especially in endemic areas such as China. The variable and nonspecific clinical features of disseminated TB often leads to an erroneous or misdiagnosis. When a patient presents with TB of the bone marrow, the clinical condition is more perplexing and the prognosis is typically poor. Till now, there is no case report after apatinib came in the market. Here, we report a case of TB of the bone marrow accompanied with SLE. The patient exhibited remarkable features, including widespread lesions in the lungs, spinal vertebrae, sacrum, and ilium that were found to be consistent with TB of the bone marrow after histopathological examination. This case highlights the importance of clinical suspicion for TB during the follow-up of SLE patients, especially in endemic areas. An aggressive diagnostic biopsy should be performed in suspected TB patients as early as possible. Wolters Kluwer Health 2016-05-06 /pmc/articles/PMC4863787/ /pubmed/27149470 http://dx.doi.org/10.1097/MD.0000000000003552 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6900
Chen, Dongying
Yang, Zheng
Yang, Ying
Zhan, Zhongping
Yang, Xiuyan
A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title_full A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title_fullStr A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title_full_unstemmed A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title_short A Rare Case of Disseminated Tuberculosis of the Bone Marrow in Systemic Lupus Erythematosus: Case Report
title_sort rare case of disseminated tuberculosis of the bone marrow in systemic lupus erythematosus: case report
topic 6900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863787/
https://www.ncbi.nlm.nih.gov/pubmed/27149470
http://dx.doi.org/10.1097/MD.0000000000003552
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