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Epigenetics of the myotonic dystrophy-associated DMPK gene neighborhood

AIM: Identify epigenetic marks in the vicinity of DMPK (linked to myotonic dystrophy, DM1) that help explain tissue-specific differences in its expression. MATERIALS & METHODS: At DMPK and its flanking genes (DMWD, SIX5, BHMG1 and RSPH6A), we analyzed many epigenetic and transcription profiles f...

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Detalles Bibliográficos
Autores principales: Buckley, Lauren, Lacey, Michelle, Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863877/
https://www.ncbi.nlm.nih.gov/pubmed/26756355
http://dx.doi.org/10.2217/epi.15.104