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Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis

Podophyllotoxin acetate (PA) acts as a radiosensitizer against non-small cell lung cancer (NSCLC) in vitro and in vivo. In this study, we examined its potential role as a chemosensitizer in conjunction with the topoisomerase inhibitors etoposide (Eto) and camptothecin (Cpt). The effects of combinati...

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Detalles Bibliográficos
Autores principales: HONG, WAN GI, CHO, JEONG HYUN, HWANG, SANG-GU, LEE, EUNAH, LEE, JAESEOK, KIM, JONG-IL, UM, HONG-DUCK, PARK, JONG KUK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863929/
https://www.ncbi.nlm.nih.gov/pubmed/27035096
http://dx.doi.org/10.3892/ijo.2016.3471