A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition

Pancreatitis-Panniculitis-Polyarthritis (PPP) syndrome is rare and its physiopathology unclear. A 6-year old boy suffered of traumatic pancreatitis complicated by PPP syndrome. Extensive investigations demonstrated high levels of pancreatic lipase and fatty acids in the affected peripheral tissues....

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Detalles Bibliográficos
Autores principales: Loverdos, Ines, Swan, Marc C., Shekherdimian, Shant, Al-Rasheed, Abdulrahman A., Schneider, Rayfel, Fish, Joel S., Ngan, Bo-Yee, Adeli, Khosrow, Lowe, Mark E., Singh, Vijay P., Sevilla, Wednesday Marie A., Langer, Jacob C., Gonska, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864014/
https://www.ncbi.nlm.nih.gov/pubmed/27182490
http://dx.doi.org/10.1016/j.epsc.2015.03.014
Descripción
Sumario:Pancreatitis-Panniculitis-Polyarthritis (PPP) syndrome is rare and its physiopathology unclear. A 6-year old boy suffered of traumatic pancreatitis complicated by PPP syndrome. Extensive investigations demonstrated high levels of pancreatic lipase and fatty acids in the affected peripheral tissues. These findings support the sequence of peripheral lipolysis and fatty acid accumulation inducing tissue inflammation.

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