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Megestrol acetate improves cardiac function in a model of cancer cachexia‐induced cardiomyopathy by autophagic modulation

BACKGROUND: Cachexia is a complex metabolic syndrome associated with cancer. One of the features of cachexia is the loss of muscle mass, characterized by an imbalance between protein synthesis and protein degradation. Muscle atrophy is caused by the hyperactivation of some of the main cellular catab...

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Detalles Bibliográficos
Autores principales: Musolino, Vincenzo, Palus, Sandra, Tschirner, Anika, Drescher, Cathleen, Gliozzi, Micaela, Carresi, Cristina, Vitale, Cristiana, Muscoli, Carolina, Doehner, Wolfram, von Haehling, Stephan, Anker, Stefan D., Mollace, Vincenzo, Springer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864048/
https://www.ncbi.nlm.nih.gov/pubmed/27239419
http://dx.doi.org/10.1002/jcsm.12116