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p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice
AIM: We investigated the pathway of autophagy signaling linked to sarcopenia of mice. METHODS: Young adult (3‐month) and aged (24‐ month) C57BL/6J mice were used. Using real‐time PCR, Western blotting, and immunohistochemical microscopy, we evaluated the amounts of p62/SQSTM1, LC3, and Beclin‐1 in t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864138/ https://www.ncbi.nlm.nih.gov/pubmed/27493873 http://dx.doi.org/10.1002/jcsm.12045 |