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Growth differentiation factor‐15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo

BACKGROUND: Loss of muscle mass is a co‐morbidity common to a range of chronic diseases including chronic obstructive pulmonary disease (COPD). Several systemic features of COPD including increased inflammatory signalling, oxidative stress, and hypoxia are known to increase the expression of growth...

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Detalles Bibliográficos
Autores principales: Patel, Mehul S., Lee, Jen, Baz, Manuel, Wells, Claire E., Bloch, Susannah, Lewis, Amy, Donaldson, Anna V., Garfield, Benjamin E., Hopkinson, Nicholas S., Natanek, Amanda, Man, William D‐C, Wells, Dominic J., Baker, Emma H., Polkey, Michael I., Kemp, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864181/
https://www.ncbi.nlm.nih.gov/pubmed/27239406
http://dx.doi.org/10.1002/jcsm.12096