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Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria

Inactivation of Kcc3 in a mixed 129/Sv×C57BL/6 mouse background has been previously found to increase systemic blood pressure (BP) through presumed neurogenic mechanisms. Yet, while this background is generally not considered ideal to investigate the cardiovascular system, KCC3 is also expressed in...

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Detalles Bibliográficos
Autores principales: Garneau, Alexandre P., Marcoux, Andrée-Anne, Noël, Micheline, Frenette-Cotton, Rachelle, Drolet, Marie-Claude, Couet, Jacques, Larivière, Richard, Isenring, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864296/
https://www.ncbi.nlm.nih.gov/pubmed/27166674
http://dx.doi.org/10.1371/journal.pone.0154398