Randomized Trial Evaluating the Impact of Ribavirin Mono-Therapy and Double Dosing on Viral Kinetics, Ribavirin Pharmacokinetics and Anemia in Hepatitis C Virus Genotype 1 Infection

In this pilot study (RibaC), 58 hepatitis C virus (HCV) genotype 1 infected treatment-naïve patients were randomized to (i) 2 weeks ribavirin double dosing concomitant with pegylated interferon-α (pegIFN-α), (ii) 4 weeks ribavirin mono-therapy prior to adding pegIFN-α, or (iii) standard-of-care (SOC...

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Detalles Bibliográficos
Autores principales: Waldenström, Jesper, Westin, Johan, Nyström, Kristina, Christensen, Peer, Dalgard, Olav, Färkkilä, Martti, Lindahl, Karin, Nilsson, Staffan, Norkrans, Gunnar, Krarup, Henrik, Norrgren, Hans, Rauning Buhl, Mads, Stenmark, Stephan, Lagging, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864304/
https://www.ncbi.nlm.nih.gov/pubmed/27167219
http://dx.doi.org/10.1371/journal.pone.0155142

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