C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

C4.4A is a modular glycolipid-anchored Ly6/uPAR/α-neurotoxin multidomain protein that exhibits a prominent membrane-associated expression in stratified squamous epithelia. C4.4A is also expressed in various solid cancer lesions, where high expression levels often are correlated to poor prognosis. Ci...

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Detalles Bibliográficos
Autores principales: Kriegbaum, Mette Camilla, Jacobsen, Benedikte, Füchtbauer, Annette, Hansen, Gert Helge, Christensen, Ib Jarle, Rundsten, Carsten Friis, Persson, Morten, Engelholm, Lars Henning, Madsen, Andreas Nygaard, Di Meo, Ivano, Lund, Ida Katrine, Holst, Birgitte, Kjaer, Andreas, Lærum, Ole Didrik, Füchtbauer, Ernst-Martin, Ploug, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864438/
https://www.ncbi.nlm.nih.gov/pubmed/27169360
http://dx.doi.org/10.1038/srep25833

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